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Structure of 1211515-00-2
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2-Bromo-3-(difluoromethyl)pyridine features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. This fluorinated pyridine derivative serves as a key building block in medicinal chemistry, enabling direct incorporation of fluorinated motifs into bioactive scaffolds under standard coupling conditions.
2-Bromo-3-(difluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions with high functional group tolerance. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the bromopyridine moiety facilitates efficient derivatization via Suzuki, Stille, or Negishi couplings. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: