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Structure of 175205-82-0
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2-Bromo-3-(trifluoromethyl)pyridine features a trifluoromethyl group flanking a brominated pyridine core, delivering enhanced electron-withdrawing character and improved metabolic stability. This structural motif enables direct incorporation into cross-coupling reactions, facilitating rapid access to functionalized heteroaryl architectures in medicinal chemistry and materials science.
2-Bromo-3-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis. The bromine moiety enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient construction of complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS06
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Signal Word : Danger
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UN#: 2926
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Class : 4.1 (6.1)
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Packing Group : Ⅲ
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Hazard Statements : H228-H300-H315-H318-H335
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Precautionary Statements : P210-P240-P241-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: