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Structure of 1211515-50-2
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2-Bromopyrimidine-4-carboxylic acid features a bromine atom at the 2-position and a carboxylic acid group at the 4-position of the pyrimidine ring, enabling selective functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and bioactive molecule frameworks, offering high reactivity under mild coupling conditions.
2-Bromopyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling. Its bromine and carboxylic acid groups offer orthogonal reactivity for late-stage diversification, while the pyrimidine core provides structural rigidity and hydrogen-bonding capacity relevant to target binding. The compound exhibits good bench stability and facilitates efficient purification by crystallization or standard chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: