6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine

Name: 6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1211516-09-4
Cat. No. CS-0050313
Purity≥95%
MDL No.MFCD08062675

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine|CS-0050313

Structure of 1211516-09-4

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Description

6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine features a brominated pyrazolopyridine core with a primary amine at the 3-position, enabling direct coupling in cross-coupling reactions. The electron-deficient heterocycle facilitates metal-catalyzed transformations, while the amine group serves as a handle for derivatization. This scaffold offers enhanced stability and solubility in polar solvents, supporting efficient synthesis of bioactive compounds.

Application

6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine serves as a versatile building block for the synthesis of biologically relevant heterocycles. The bromine and amino groups enable efficient late-stage functionalization via palladium-catalyzed cross-coupling and electrophilic substitution reactions. Its bench-stable nature and compatibility with diverse reaction conditions facilitate rapid access to pyrazolopyridine-based scaffolds used in medicinal chemistry and agrochemical research.

General Information

CAS No. 1211516-09-4
Cat. No. CS-0050313
Purity ≥95%
MDL No. MFCD08062675
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅BrN₄
Molecular Weight 213.04
Synonym(s) None
SMILES NC1=NNC2=CC(Br)=CN=C12

Computational Chemistry Data

TPSA 67.59
LogP 1.3026
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine

CAS No. 1211516-09-4

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