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Structure of 1211526-95-2
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4-Bromo-6-methoxypyridin-2-amine features a pyridine core with strategically positioned bromo and methoxy groups, enabling selective coupling in cross-coupling reactions. The electron-rich amine facilitates efficient functionalization, while the ortho-bromo substitution enhances reactivity under palladium catalysis. This bench-stable intermediate integrates readily into complex heterocyclic scaffolds for medicinal chemistry applications.
4-Bromo-6-methoxypyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds through palladium-catalyzed cross-coupling reactions. The bromo group facilitates reliable Suzuki, Buchwald–Hartwig, and Negishi couplings, while the ortho-amino and methoxy functionalities provide complementary sites for further derivatization. Its bench-stable nature and straightforward purification support scalable synthesis and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: