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Structure of 1212021-62-9
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This boronic acid features a cyano group and trifluoromethyl substituent positioned ortho to the boronate, delivering enhanced stability and electron-withdrawing character. The combination enables efficient Suzuki-Miyaura coupling under standard conditions, facilitating rapid access to complex heteroaryl architectures in medicinal chemistry and materials science.
(3-Cyano-5-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced electronic and metabolic stability. The cyano and trifluoromethyl groups confer high functional group tolerance and improved solubility, while the boronic acid moiety exhibits excellent bench stability and compatibility with standard reaction conditions. Its predictable reactivity facilitates rapid access to complex heterocyclic and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: