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Structure of 3430-22-6
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3-Bromo-4-methylpyridine is a halogenated pyridine derivative featuring a methyl group at the 4-position and a bromine substituent at the 3-position. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to construct complex nitrogen-containing scaffolds. The molecule exhibits enhanced reactivity due to the combined influence of the electron-withdrawing bromine and adjacent electron-donating methyl group.
3-Bromo-4-methylpyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity profile. The bromine substituent provides reliable functionalization potential, while the methyl group enhances electron density at the pyridine ring, improving regioselectivity in subsequent transformations. Its bench-stable nature and compatibility with standard purification methods make it ideal for modular heterocycle construction and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: