(S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine

Name: (S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1212972-62-7
Cat. No. CS-0112780
Purity≥96%
MDL No.MFCD07373977

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine|CS-0112780

Structure of 1212972-62-7

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Description

(S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine is a chiral amine scaffold featuring a fluorinated tetralin core with defined stereochemistry at the nitrogen-bearing carbon. This bench-stable, moisture-tolerant building block integrates readily into asymmetric synthesis workflows, enabling access to biologically relevant heterocycles and pharmaceutical intermediates through straightforward derivatization.

Application

(S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine serves as a chiral building block for the synthesis of bioactive molecules, offering enhanced metabolic stability and defined stereochemistry. Its fluorinated tetralin core provides favorable lipophilicity and rigidity, enabling efficient incorporation into pharmaceutical scaffolds. The primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions, while the bench-stable, crystalline solid form supports reliable handling and purification in synthetic workflows.

General Information

CAS No. 1212972-62-7
Cat. No. CS-0112780
Purity ≥96%
MDL No. MFCD07373977
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂FN
Molecular Weight 165.21
Synonym(s) None
SMILES N[C@H]1CCCC2=C1C=CC=C2F

Computational Chemistry Data

TPSA 26.02
LogP 2.1618
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine

CAS No. 1212972-62-7

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