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(R)-2-Amino-2-(3-fluoro-5-methoxyphenyl)ethan-1-ol

  • CAS No. 1213343-02-2

  • Cat. No. CS-0188043
  • Molecule weight185.20
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-2-Amino-2-(3-fluoro-5-methoxyphenyl)ethan-1-ol|CS-0188043

Structure of 1213343-02-2

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General Information

  • CAS No. 1213343-02-2
  • Cat. No. CS-0188043
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂FNO₂
  • Molecular Weight 185.20
  • Synonym(s) None
  • SMILES [C@@H](CO)(N)C1=CC(OC)=CC(F)=C1

Description

This chiral building block features a (R)-configured amino alcohol scaffold flanked by a 3-fluoro-5-methoxyphenyl group, delivering enhanced solubility and stability under standard bench conditions. The electron-rich aromatic ring and polar functional groups enable efficient coupling in asymmetric synthesis, while the stereochemical integrity supports high-fidelity incorporation into complex molecular architectures.

Application

(R)-2-Amino-2-(3-fluoro-5-methoxyphenyl)ethan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established amine and alcohol functional group transformations. Its bench-stable nature, combined with orthogonal reactivity and tolerance to standard coupling conditions, facilitates efficient incorporation into diverse heterocyclic scaffolds and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   55.48
  • LogP   0.8264
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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