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CS-W001157 4
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2-(5-Methoxypyridin-2-yl)acetic acid

  • CAS No. 1214332-39-4

  • Cat. No. CS-0062008
  • Molecule weightNone
  • Purity≥96%
  • MDL No.MFCD13194538

*For research and further manufacturing use only, not for direct human use.

2-(5-Methoxypyridin-2-yl)acetic acid|CS-0062008

Structure of 1214332-39-4

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General Information

  • CAS No. 1214332-39-4
  • Cat. No. CS-0062008
  • Purity ≥96%
  • MDL No. MFCD13194538
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight None
  • Synonym(s) 5-Methoxy-2-pyridineacetic acid
  • SMILES COC1=CN=C(C=C1)CC(=O)O

Description

This pyridine-based carboxylic acid features a methoxy-substituted heterocycle that enhances solubility and metabolic stability. The acetic acid side chain enables direct coupling to amines or incorporation into peptide scaffolds. Designed for synthetic versatility in medicinal chemistry, it serves as a robust building block for bioactive molecule assembly under standard conditions.

Application

2-(5-Methoxypyridin-2-yl)acetic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through established coupling and functionalization protocols. Its pyridine-carboxylic acid motif offers enhanced solubility and metabolic stability, while the methoxy group provides moderate electronic tuning and orthogonal reactivity. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.7173
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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