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Structure of 1214345-17-1
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6-Bromo-2-fluoronicotinic acid is a halogenated pyridine carboxylic acid featuring strategically positioned bromo and fluoro substituents at the 6- and 2-positions, respectively. This electronic modulation enhances reactivity in cross-coupling transformations. The carboxylic acid group enables direct derivatization or incorporation into bioactive scaffolds. Bench-stable and moisture-tolerant, it facilitates efficient synthesis of functionalized heterocycles under standard conditions.
6-Bromo-2-fluoronicotinic acid serves as a versatile building block for the synthesis of fluorinated heterocycles and bioactive molecules. Its dual halogenation pattern enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates direct amidation or esterification. The compound exhibits good bench stability and is readily purified by recrystallization, making it suitable for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: