6-Bromo-4-chloropyrido[2,3-d]pyrimidine

Name: 6-Bromo-4-chloropyrido[2,3-d]pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1215787-31-7
Cat. No. CS-W022462
Purity≥95%
MDL No.MFCD11040200

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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6-Bromo-4-chloropyrido[2,3-d]pyrimidine|CS-W022462

Structure of 1215787-31-7

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Description

6-Bromo-4-chloropyrido[2,3-d]pyrimidine is a heterocyclic building block featuring bromo and chloro substituents at electron-rich positions, enabling selective cross-coupling reactions. This bench-stable scaffold integrates readily into kinase inhibitors and pharmaceutical intermediates, offering enhanced reactivity in palladium-catalyzed transformations.

Application

6-Bromo-4-chloropyrido[2,3-d]pyrimidine serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its dual halogenation pattern enables selective cross-coupling reactions via Pd-catalyzed methodologies, facilitating efficient construction of complex scaffolds. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, supporting broad functional group tolerance and straightforward purification.

General Information

CAS No. 1215787-31-7
Cat. No. CS-W022462
Purity ≥95%
MDL No. MFCD11040200
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₃BrClN₃
Molecular Weight 244.48
Synonym(s) None
SMILES BrC2=CC1=C(N=CN=C1Cl)N=C2

Computational Chemistry Data

TPSA 38.67
LogP 2.4407
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

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6-Bromo-4-chloropyrido[2,3-d]pyrimidine

CAS No. 1215787-31-7

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