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Structure of 1216012-87-1
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2-Methyloxazole-5-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 5-position and a methyl substituent at the 2-position. This electron-deficient oxazole scaffold enables direct integration into bioactive molecules, offering enhanced metabolic stability and favorable solubility profiles in polar organic solvents.
2-Methyloxazole-5-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to oxazole-containing scaffolds via standard coupling and functionalization protocols. Its carboxylic acid group facilitates amide bond formation and derivatization under mild conditions, while the methyl substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis campaigns targeting bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: