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Structure of 172215-91-7
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3-Bromo-4-(trifluoromethyl)aniline features a strategically positioned trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the bromo substituent enables facile cross-coupling reactions. This compound serves as a key building block in the synthesis of functionalized arylamines for pharmaceutical and agrochemical applications.
3-Bromo-4-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Buchwald-Hartwig arylations. The bromo group facilitates efficient functionalization, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Bench-stable and readily purified by recrystallization or column chromatography, it functions reliably in multi-step syntheses of complex heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: