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2-Amino-N-(2-(dimethylamino)ethyl)-2-methylpropanamide dihydrochloride

  • CAS No. 1219957-57-9

  • Cat. No. CS-0085637
  • Purity≥97%
  • MDL No.MFCD13562564

*For research and further manufacturing use only, not for direct human use.

2-Amino-N-(2-(dimethylamino)ethyl)-2-methylpropanamide dihydrochloride|CS-0085637

Structure of 1219957-57-9

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General Information

  • CAS No. 1219957-57-9
  • Cat. No. CS-0085637
  • Purity ≥97%
  • MDL No. MFCD13562564
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₂₁Cl₂N₃O
  • Molecular Weight 246.18
  • Synonym(s) 2-Amino-N-[2-(dimethylamino)ethyl]-2-methylpropanamide dihydrochloride
  • SMILES CC(C)(N)C(NCCN(C)C)=O.[H]Cl.[H]Cl

Description

This dihydrochloride salt features a tertiary amine-bearing side chain appended to a sterically hindered amide core, delivering enhanced solubility and stability under standard conditions. The protonated dimethylamino group enables efficient charge-based purification and facilitates incorporation into peptide-based conjugates or bioactive scaffolds.

Application

This compound serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive amide and heterocyclic scaffolds. Its bifunctional structure—featuring a primary amine and a tertiary amine—facilitates efficient coupling reactions and salt formation, enhancing solubility and stability. The dihydrochloride salt form improves handling and shelf life, while the methylated propanamide core provides steric and electronic tuning for target-directed synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.36
  • LogP   0.2451
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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