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Structure of 1220696-53-6
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1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole is a bench-stable boronate ester featuring a sterically protected dioxaborolane group. This indazole scaffold integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, enabling efficient C–C bond formation with aryl and heteroaryl halides. The tetramethyl-substituted boronate moiety enhances stability and minimizes protodeboronation, facilitating reliable cross-coupling in complex molecular architectures.
1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the indazole core provides a stable, nitrogen-rich scaffold relevant to medicinal chemistry. Bench-stable and easily handled, it facilitates rapid diversification of indazole-based architectures in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: