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Structure of 1224885-47-5
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2-Bromopyrimidine-5-carboxylic acid features a bromine atom at the 2-position and a carboxylic acid group at the 5-position on a pyrimidine scaffold. This combination enables direct functionalization in cross-coupling reactions and facilitates conjugation to biomolecules via amide bond formation. The electron-deficient pyrimidine ring enhances reactivity in nucleophilic substitution processes.
2-Bromopyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. Its carboxylic acid group facilitates derivatization through amide formation or esterification, while the pyrimidine core provides a stable scaffold for further structural elaboration. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: