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CS-W001157 4
Total: USD 88.00

tert-Butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

  • CAS No. 203661-69-2

  • Cat. No. CS-W007836
  • Purity≥97%
  • MDL No.MFCD12198552
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate|CS-W007836

Structure of 203661-69-2

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Description

tert-Butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate is a sterically hindered spirocyclic lactam precursor featuring a bench-stable tert-butyl ester and a ketone at the 2-position. This scaffold integrates readily into complex heterocycles, enabling efficient access to nitrogen-rich frameworks in medicinal chemistry and natural product synthesis.

Application

tert-Butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry and catalytic synthesis. The molecule features a stable, sterically hindered spirocyclic core with orthogonal functional groups: a ketone at C2 and a tert-butyl ester at C7. This combination enables selective transformations including reductive amination, nucleophilic addition, and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification methods make it ideal for iterative synthesis of complex heterocycles and drug-like scaffolds.

General Information

  • CAS No. 203661-69-2
  • Cat. No. CS-W007836
  • Purity ≥97%
  • MDL No. MFCD12198552
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₁NO₃
  • Molecular Weight 239.32
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCC2(CC(=O)C2)CC1

Computational Chemistry Data

  • TPSA   46.61
  • LogP   2.3666
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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