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Structure of 122509-73-3
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4,5-Dichloro-1H-indole features a rigid, electron-deficient indole core with chlorines at the 4 and 5 positions, enhancing its utility in heterocyclic synthesis. This bench-stable derivative integrates readily into pharmaceutical scaffolds and serves as a key intermediate in constructing bioactive molecules via cross-coupling and electrophilic substitution reactions.
4,5-Dichloro-1H-indole serves as a valuable building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. The dichloro substitution pattern enhances electrophilic reactivity at C4 and C5, enabling straightforward functionalization via palladium-catalyzed coupling reactions. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: