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Structure of 121859-57-2
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5,6-Dichloro-1H-indole features two chlorine atoms positioned at the 5 and 6 ring junctions of the indole scaffold, enhancing its electron-deficient character. This substitution pattern improves stability and facilitates electrophilic functionalization in synthetic workflows. The compound serves as a key building block for bioactive heterocycles and pharmaceutical intermediates.
5,6-Dichloro-1H-indole serves as a versatile building block for the synthesis of substituted indoles and heterocyclic scaffolds. Its dichloro substitution enhances electrophilic reactivity at C5 and C6, facilitating palladium-catalyzed cross-coupling reactions and direct functionalization. The compound exhibits good bench stability and ease of purification, making it suitable for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: