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Structure of 1226985-35-8
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5-Iodo-1-methyl-1H-indazol-3-ol features a sterically hindered indazol-3-ol core with a strategically positioned iodine atom, enabling efficient cross-coupling reactions. The methyl group enhances solubility and metabolic stability, while the phenolic hydroxyl supports hydrogen bonding in target engagement. This scaffold delivers robust performance in medicinal chemistry campaigns requiring bioorthogonal functionalization.
5-Iodo-1-methyl-1H-indazol-3-ol serves as a versatile building block for the synthesis of biologically active indazolyl scaffolds. The iodine substituent enables reliable palladium-catalyzed cross-coupling reactions, while the phenolic hydroxyl group offers opportunities for derivatization or protection. Bench-stable and readily purified, it functions effectively in standard coupling protocols and supports the construction of complex heterocyclic architectures relevant to medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: