3-Chloro-2-pyrazinamine

Name: 3-Chloro-2-pyrazinamine
Brand: ChemScene
Availability: InStock
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CAS No. 6863-73-6
Cat. No. CS-W007499
Purity≥96%
MDL No.MFCD04114305

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

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Description

3-Chloro-2-pyrazinamine features a chlorinated pyrazine core with a primary amine at the adjacent position, enabling direct incorporation into heterocyclic scaffolds. This bench-stable derivative supports efficient functionalization in medicinal chemistry and materials synthesis.

Application

3-Chloro-2-pyrazinamine serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazine-based heterocycles common in kinase inhibitors and antimicrobial agents. Its dual functionality—reactive amine and electrophilic chloro group—facilitates sequential derivatization via nucleophilic substitution or coupling reactions. Bench-stable and readily purified, it functions effectively in standard synthetic workflows for API development and scaffold diversification.

General Information

CAS No. 6863-73-6
Cat. No. CS-W007499
Purity ≥96%
MDL No. MFCD04114305
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₄ClN₃
Molecular Weight 129.55
Synonym(s) 2-Amino-3-chloropyrazine
SMILES ClC(N=CC=N1)=C1N

Computational Chemistry Data

TPSA 51.8
LogP 0.7122
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

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3-Chloro-2-pyrazinamine

CAS No. 6863-73-6

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