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Structure of 1227210-35-6
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1-Bromo-4-fluoro-2-methyl-3-nitrobenzene features a densely functionalized aromatic core with orthogonal reactivity. The bromine enables palladium-catalyzed cross-coupling, while the fluorine supports nucleophilic substitution under mild conditions. The para-fluoro and ortho-methyl groups modulate electronic distribution and steric accessibility, enhancing selectivity in complex synthesis. This compound serves as a key intermediate for pharmaceuticals and advanced materials.
1-Bromo-4-fluoro-2-methyl-3-nitrobenzene serves as a versatile building block for the synthesis of functionalized aromatic scaffolds. The molecule enables palladium-catalyzed cross-coupling reactions due to its bromo substituent, while the fluoro and nitro groups offer orthogonal reactivity for sequential transformations. Its bench-stable nature and compatibility with standard synthetic protocols make it suitable for medicinal chemistry and process development workflows requiring precise regiocontrol.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: