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Structure of 1227918-06-0
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4-Bromo-2-fluoro-6-hydroxybenzonitrile features a trifunctional aromatic core with bromine, fluorine, and hydroxyl groups positioned ortho to one another, enabling selective derivatization. The nitrile moiety provides a polar handle for downstream coupling reactions. This bench-stable compound serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized aryl scaffolds.
4-Bromo-2-fluoro-6-hydroxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the phenolic hydroxyl group and selective substitution at the bromo and fluoro positions. Its compatibility with palladium-catalyzed cross-coupling reactions and orthogonality of reactive sites facilitates efficient synthesis of complex heterocyclic scaffolds and API intermediates. The compound exhibits good bench stability and is amenable to standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: