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Structure of 1228898-36-9
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3-Fluoro-2-methoxypyridin-4-amine features a pyridine core with strategically positioned fluorine and methoxy groups, enabling enhanced electronic modulation and metabolic stability. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds, offering improved solubility and targeted binding affinity in medicinal chemistry applications.
3-Fluoro-2-methoxypyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based pharmacophores. The molecule combines an electrophilic fluorine at C3 with a nucleophilic amine at C4 and a methoxy group at C2, offering orthogonal reactivity for Suzuki-Miyaura coupling, Buchwald-Hartwig amination, and directed metalation. Its bench stability and compatibility with diverse reaction conditions facilitate rapid scaffold diversification in API discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: