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Structure of 1232431-41-2
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3-Bromo-6-fluoro-2-pyridinamine features a strategically positioned bromo and fluoro substitution on the pyridine ring, enabling directed metalation and cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and functional materials, offering enhanced reactivity under standard conditions.
3-Bromo-6-fluoro-2-pyridinamine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions due to its compatible halogen functionality. The ortho-amino group facilitates directed metallation and further functionalization, while the fluorine substituent enhances metabolic stability and modulates electronic properties in pharmaceutical scaffolds. Bench-stable and amenable to standard purification techniques, it functions effectively in multi-step synthetic sequences requiring precise regiocontrol.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: