2,6-Dichloro-3-iodopyridin-4-amine

Name: 2,6-Dichloro-3-iodopyridin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 1235873-11-6
Cat. No. CS-0062153
Purity≥95%
MDL No.MFCD29918898

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2,6-Dichloro-3-iodopyridin-4-amine|CS-0062153

Structure of 1235873-11-6

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Description

2,6-Dichloro-3-iodopyridin-4-amine serves as a key electrophilic building block in the synthesis of advanced heterocyclic compounds. The iodine substituent enables efficient cross-coupling reactions, while the dichloro pattern enhances reactivity and modulates electronic properties. This bench-stable, moisture-tolerant reagent integrates readily into pharmaceutical and agrochemical development workflows.

Application

2,6-Dichloro-3-iodopyridin-4-amine serves as a versatile building block for constructing substituted pyridine scaffolds in medicinal chemistry and catalytic cross-coupling reactions. The dichloro substitution pattern enables selective functionalization via palladium-catalyzed coupling, while the iodine moiety provides high reactivity in Suzuki, Stille, and Negishi transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for modular synthesis of complex heterocyclic systems.

General Information

CAS No. 1235873-11-6
Cat. No. CS-0062153
Purity ≥95%
MDL No. MFCD29918898
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃Cl₂IN₂
Molecular Weight None
Synonym(s) 4-Pyridinamine,2,6-dichloro-3-iodo-（WS205023）
SMILES NC1=C(I)C(Cl)=NC(Cl)=C1

Computational Chemistry Data

TPSA 38.91
LogP 2.5752
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dichloro-3-iodopyridin-4-amine

CAS No. 1235873-11-6

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