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Structure of 1236033-34-3
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This pyrrolidine derivative features a bulky silyl-protected hydroxyl group, enabling stable handling and compatibility with sensitive coupling reactions. The diphenylmethyl moiety enhances solubility in organic media, while the chiral (2R) configuration ensures stereocontrolled synthesis in complex molecule assembly.
(2R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]pyrrolidine serves as a robust chiral auxiliary in asymmetric synthesis, enabling stereoselective transformations via its protected amine and silyl ether functionalities. The bulky tert-dimethylsilyl group provides excellent steric shielding and bench stability, while the diphenylmethyl (DMP) moiety facilitates purification by chromatography. This scaffold functions effectively in enantioselective alkylation and conjugate addition protocols, offering predictable stereocontrol and compatibility with standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: