2,5-Dibromopyridin-3-amine

Name: 2,5-Dibromopyridin-3-amine
Brand: ChemScene
Availability: InStock
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CAS No. 90902-84-4
Cat. No. CS-0052143
Purity≥98%
MDL No.MFCD09266224

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 90902-84-4

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Description

2,5-Dibromopyridin-3-amine features a pyridine core with bromine substituents at the 2 and 5 positions and an amino group at C3, enabling efficient coupling in cross-coupling reactions. This electron-deficient scaffold integrates readily into heterocyclic architectures, offering high reactivity under palladium catalysis and stability under standard bench conditions.

Application

2,5-Dibromopyridin-3-amine serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal bromine reactivity. The pyridin-3-amine core provides a handle for further functionalization via electrophilic substitution or metal-mediated transformations. Its bench-stable crystalline form facilitates handling and purification, while the presence of two halogen sites supports sequential derivatization strategies in the synthesis of complex heterocyclic scaffolds and pharmaceutical intermediates.

General Information

CAS No. 90902-84-4
Cat. No. CS-0052143
Purity ≥98%
MDL No. MFCD09266224
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄Br₂N₂
Molecular Weight 251.91
Synonym(s) 2,5-DIBROMO-3-AMINOPYRIDINE
SMILES NC1=CC(Br)=CN=C1Br

Computational Chemistry Data

TPSA 38.91
LogP 2.1888
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H318
Precautionary Statements : P264-P270-P330-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,5-Dibromopyridin-3-amine

CAS No. 90902-84-4

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