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Structure of 124045-51-8
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tert-Butyl methyl(prop-2-yn-1-yl)carbamate features a propargylic carbamate moiety flanked by a tert-butyl group and a methyl-substituted alkyne, enabling selective protection of amines under mild conditions. This stable, bench-ready reagent integrates seamlessly into multistep syntheses, delivering efficient deprotection via acidolysis without affecting other functional groups.
tert-Butyl methyl(prop-2-yn-1-yl)carbamate serves as a versatile, bench-stable carbamate protecting group for amines, enabling orthogonal protection in complex molecule synthesis. Its propargylic linkage facilitates selective deprotection under mild conditions and supports efficient coupling reactions via the alkyne handle. The compound exhibits excellent functional group tolerance and simplifies purification in multistep synthetic sequences, making it well-suited for peptide derivatization and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: