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CS-W001157 4
Total: USD 88.00

tert-Butyl methyl(prop-2-yn-1-yl)carbamate

  • CAS No. 124045-51-8

  • Cat. No. CS-0142817
  • Purity≥95%
  • MDL No.MFCD22548360
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl methyl(prop-2-yn-1-yl)carbamate|CS-0142817

Structure of 124045-51-8

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Description

tert-Butyl methyl(prop-2-yn-1-yl)carbamate features a propargylic carbamate moiety flanked by a tert-butyl group and a methyl-substituted alkyne, enabling selective protection of amines under mild conditions. This stable, bench-ready reagent integrates seamlessly into multistep syntheses, delivering efficient deprotection via acidolysis without affecting other functional groups.

Application

tert-Butyl methyl(prop-2-yn-1-yl)carbamate serves as a versatile, bench-stable carbamate protecting group for amines, enabling orthogonal protection in complex molecule synthesis. Its propargylic linkage facilitates selective deprotection under mild conditions and supports efficient coupling reactions via the alkyne handle. The compound exhibits excellent functional group tolerance and simplifies purification in multistep synthetic sequences, making it well-suited for peptide derivatization and heterocycle construction.

General Information

  • CAS No. 124045-51-8
  • Cat. No. CS-0142817
  • Purity ≥95%
  • MDL No. MFCD22548360
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NO₂
  • Molecular Weight 169.22
  • Synonym(s) tert-butyl N-methyl-N-prop-2-ynylcarbamate
  • SMILES O=C(OC(C)(C)C)N(C)CC#C

Computational Chemistry Data

  • TPSA   29.54
  • LogP   1.4865
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

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