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CS-W001157 4
Total: USD 88.00

2,5-Dichloropyrimidine-4-carboxylic acid

  • CAS No. 1240594-41-5

  • Cat. No. CS-0643041
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Dichloropyrimidine-4-carboxylic acid|CS-0643041

Structure of 1240594-41-5

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General Information

  • CAS No. 1240594-41-5
  • Cat. No. CS-0643041
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Cl₂N₂O₂
  • Molecular Weight 192.99
  • Synonym(s) None
  • SMILES O=C(C1=NC(Cl)=NC=C1Cl)O

Description

2,5-Dichloropyrimidine-4-carboxylic acid features a rigid pyrimidine core bearing two chlorine substituents and a carboxylic acid group, enabling direct integration into heterocyclic scaffolds. The electron-deficient ring facilitates nucleophilic substitution, while the carboxylic acid offers versatility in amide coupling and derivatization under standard conditions. This compound serves as a key building block for pharmaceutical intermediates and functional materials.

Application

2,5-Dichloropyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its dichloro-substituted pyrimidine core enables efficient functionalization via nucleophilic substitution, while the carboxylic acid group facilitates coupling reactions and derivatization. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for use in API intermediate development and targeted library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.4816
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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