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CS-W001157 4
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Ethyl 2-(pyrimidin-4-yl)acetate

  • CAS No. 1240606-58-9

  • Cat. No. CS-0054939
  • Molecule weight166.18
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(pyrimidin-4-yl)acetate|CS-0054939

Structure of 1240606-58-9

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General Information

  • CAS No. 1240606-58-9
  • Cat. No. CS-0054939
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) PyriMidin-4-Yl-Acetic Acid Ethyl Ester
  • SMILES CCOC(=O)CC1=CC=NC=N1

Description

Ethyl 2-(pyrimidin-4-yl)acetate is a bench-stable, moisture-tolerant building block featuring a pyrimidine ring linked to an ethyl acetic acid ester. This configuration enables direct integration into pharmaceutical intermediates and functional materials via nucleophilic substitution or coupling reactions.

Application

Ethyl 2-(pyrimidin-4-yl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-containing scaffolds via standard functional group transformations. Its ethyl ester moiety facilitates nucleophilic acyl substitution and reduction, while the pyrimidin-4-yl group provides a robust heterocyclic core for further derivatization. The compound exhibits excellent bench stability and is compatible with common reaction conditions, simplifying purification and integration into multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.08
  • LogP   0.5822
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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