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CS-W001157 4
Total: USD 88.00

2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 124215-44-7

  • Cat. No. CS-0174363
  • Molecule weight248.95
  • Purity≥96%
  • MDL No.MFCD10567053

*For research and further manufacturing use only, not for direct human use.

2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0174363

Structure of 124215-44-7

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General Information

  • CAS No. 124215-44-7
  • Cat. No. CS-0174363
  • Purity ≥96%
  • MDL No. MFCD10567053
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈BBrO₂
  • Molecular Weight 248.95
  • Synonym(s) 3-Bromopropylboronic acid pinacol ester
  • SMILES CC1(C(C)(OB(O1)CCCBr)C)C

Description

This boronate ester features a bromoalkyl side chain enabling direct functionalization in cross-coupling reactions. The tetramethyl-substituted dioxaborolane ring imparts exceptional stability and solubility under standard conditions, facilitating efficient incorporation into complex molecular architectures without decomposition.

Synthesis

  • Route1
    • null|null
      627-15-6
    • null|null
      25015-63-8
    • ~67%
    • In-stock
      2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0174363
      124215-44-7

    References

    • Colin, Sylvie; Vaysse-Ludot, Lucile; Lecouve, Jean-Pierre; Maddaluno, Jacques Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4505 - 4511
  • Route2
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      90084-34-7
    • ~%
    • In-stock
      2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0174363
      124215-44-7

    References

    • US2005/70459 A1, ; Page/Page column 23 ;
  • Route3
    • (E)-1,3-Dibromoprop-1-ene|CS-1639171
      32121-07-6
    • null|null
      25015-63-8
    • ~75%
    • In-stock
      2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0174363
      124215-44-7

    References

    • Colin, Sylvie; Vaysse-Ludot, Lucile; Lecouve, Jean-Pierre; Maddaluno, Jacques Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4505 - 4511

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.8636
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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