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tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity

  • CAS No. 124655-09-0

  • Cat. No. CS-0228748
  • Purity≥98%
  • MDL No.MFCD08063915

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity|CS-0228748

Structure of 124655-09-0

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General Information

  • CAS No. 124655-09-0
  • Cat. No. CS-0228748
  • Purity ≥98%
  • MDL No. MFCD08063915
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄O₅
  • Molecular Weight 260.33
  • Synonym(s) Tert-Butyl[(4R,6R)-6-Hydroxymethyl-1,3-Dioxan-4-Yl]Acetate
  • SMILES CC(C)(C)OC(C[C@H]1C[C@@H](CO)OC(C)(C)O1)=O

Synthesis

  • Route1
    • null|null
      151140-38-4
    • ~99%
    • tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity|CS-0228748
      124655-09-0

    References

    • Synthesis, , # 8 p. 1014 - 1018
  • Route2

    References

    • US5278313 A1, ;
  • Route3
    • tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482
      124752-23-4
    • ~81%
    • tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity|CS-0228748
      124655-09-0

    References

    • Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.99
  • LogP   1.6207
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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