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CS-W001157 4
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tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity

  • CAS No. 124752-23-4

  • Cat. No. CS-0167482
  • Purity≥97%
  • MDL No.MFCD02093270

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482

Structure of 124752-23-4

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General Information

  • CAS No. 124752-23-4
  • Cat. No. CS-0167482
  • Purity ≥97%
  • MDL No. MFCD02093270
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₂O₅
  • Molecular Weight 258.31
  • Synonym(s) None
  • SMILES O=C(C[C@@H]1OC(C)(O[C@@H](C1)C=O)C)OC(C)(C)C

Synthesis

  • Route1
    • tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity|CS-0228748
      124655-09-0
    • ~94%
    • tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482
      124752-23-4

    References

    • Tetrahedron Letters, , vol. 31, # 18 p. 2545 - 2548
  • Route2
    • null|null
      147489-02-9
    • ~86%
    • tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482
      124752-23-4

    References

    • Tetrahedron Letters, , vol. 34, # 3 p. 513 - 516
  • Route3
    • null|null
      79-37-8
    • tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate Atorvastatin calcium Impurity|CS-0228748
      124655-09-0
    • ~%
    • tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482
      124752-23-4

    References

    • US4970313 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.83
  • LogP   1.8273
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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