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Structure of 1250994-14-9
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tert-Butyl 2-oxo-8-azaspiro[4.5]decane-8-carboxylate is a sterically shielded spirocyclic carbamate featuring a ketone and a latent amine within a rigid 8-azaspiro[4.5]decane framework. This bench-stable, moisture-tolerant building block enables efficient access to complex nitrogen-containing scaffolds in medicinal chemistry and natural product synthesis.
tert-Butyl 2-oxo-8-azaspiro[4.5]decane-8-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and natural product synthesis. The constrained spirocyclic framework imparts rigidity, while the ketone and ester functionalities enable selective functionalization via enolate chemistry, reductive amination, or nucleophilic addition. Bench-stable and amenable to standard purification methods, it facilitates efficient access to complex nitrogen-containing scaffolds relevant to drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: