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Structure of 1251006-73-1
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tert-Butyl 3-(piperidin-3-yl)azetidine-1-carboxylate features a strained azetidine ring fused to a piperidine moiety, delivering enhanced metabolic stability and improved membrane permeability. This scaffold integrates readily into medicinal chemistry campaigns targeting CNS disorders and kinase inhibitors, offering high functional group tolerance and compatibility with standard coupling protocols.
tert-Butyl 3-(piperidin-3-yl)azetidine-1-carboxylate serves as a versatile scaffold for medicinal chemistry campaigns, enabling rapid access to constrained azetidine-containing analogs. The tert-butyl carbamate group provides excellent bench stability and orthogonal deprotection compatibility, while the piperidin-3-yl moiety offers favorable conformational preorganization and hydrogen-bonding capacity. This compound facilitates efficient late-stage diversification via standard coupling reactions and functions as a key building block in the synthesis of bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: