7-Bromoimidazo[1,2-a]pyrimidine

Name: 7-Bromoimidazo[1,2-a]pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1251033-57-4
Cat. No. CS-0155556
Purity≥97%
MDL No.MFCD16877232

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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7-Bromoimidazo[1,2-a]pyrimidine|CS-0155556

Structure of 1251033-57-4

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Description

7-Bromoimidazo[1,2-a]pyrimidine is a bench-stable heterocyclic scaffold featuring a bromine substituent at the 7-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient core integrates efficiently into bioactive molecules and serves as a key building block for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

7-Bromoimidazo[1,2-a]pyrimidine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct functionalization at the C7 position via palladium-catalyzed cross-coupling reactions. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient access to imidazopyrimidine-based scaffolds commonly found in kinase inhibitors and pharmaceutical intermediates.

General Information

CAS No. 1251033-57-4
Cat. No. CS-0155556
Purity ≥97%
MDL No. MFCD16877232
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄BrN₃
Molecular Weight 198.02
Synonym(s) None
SMILES C1=CN2C=CN=C2N=C1Br

Computational Chemistry Data

TPSA 30.19
LogP 1.4918
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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7-Bromoimidazo[1,2-a]pyrimidine

CAS No. 1251033-57-4

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