Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-[[3,5-Bis(trifluoroMethyl)phenyl]aMino]-4-[[(8a,9S)-6'-Methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

  • CAS No. 1256245-84-7

  • Cat. No. CS-0051570
  • Purity≥97%
  • MDL No.MFCD30802180
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-[[3,5-Bis(trifluoroMethyl)phenyl]aMino]-4-[[(8a,9S)-6'-Methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione|CS-0051570

Structure of 1256245-84-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

This cyclobutenedione features a trifluoromethylated aryl amine and a methoxycinchonan amino moiety, combining electron-deficient character with stereochemically defined heterocyclic architecture. The structure integrates a rigid, functionalized scaffold suitable for targeted molecular design in medicinal chemistry applications.

Application

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8a,9S)-6'-Methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione serves as a versatile scaffold for medicinal chemistry campaigns, leveraging the electron-deficient cyclobutenedione core for conjugate addition reactions. The trifluoromethyl aryl amine and cinchona-derived tertiary amine enable orthogonal functionalization, while the methoxy-substituted quinoline framework supports hydrogen bonding and solubility modulation. Bench-stable and amenable to purification by standard chromatographic methods, it facilitates rapid access to complex heterocyclic architectures in API lead optimization.

General Information

  • CAS No. 1256245-84-7
  • Cat. No. CS-0051570
  • Purity ≥97%
  • MDL No. MFCD30802180
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₂H₂₈F₆N₄O₃
  • Molecular Weight 630.58
  • Synonym(s) 9S)-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1
  • SMILES C=C[C@H]1[C@@]2([H])CC[N@@](C1)[C@@]([C@@H](NC(C3=O)=C(NC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C3=O)C5=C(C=C(OC)C=C6)C6=NC=C5)([H])C2

Computational Chemistry Data

  • TPSA   83.56
  • LogP   6.6702
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   8

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1256245-84-7 sigma1256245-84-7 manufacturer1256245-84-7 price1256245-84-7 structure1256245-84-7 SDSbuy 1256245-84-71256245-84-7 supplier1256245-84-7 uses1256245-84-7 molecular weightprice of 1256245-84-71256245-84-7 chemical name formula of 1256245-84-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label