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Structure of 1256245-84-7
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This cyclobutenedione features a trifluoromethylated aryl amine and a methoxycinchonan amino moiety, combining electron-deficient character with stereochemically defined heterocyclic architecture. The structure integrates a rigid, functionalized scaffold suitable for targeted molecular design in medicinal chemistry applications.
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8a,9S)-6'-Methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione serves as a versatile scaffold for medicinal chemistry campaigns, leveraging the electron-deficient cyclobutenedione core for conjugate addition reactions. The trifluoromethyl aryl amine and cinchona-derived tertiary amine enable orthogonal functionalization, while the methoxy-substituted quinoline framework supports hydrogen bonding and solubility modulation. Bench-stable and amenable to purification by standard chromatographic methods, it facilitates rapid access to complex heterocyclic architectures in API lead optimization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P280-P302+P352
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Lot numbers can be found on the outside label of a product: