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Structure of 620960-26-1
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This thiourea derivative features a sterically hindered cyclohexyl amine moiety paired with a strongly electron-deficient aryl group, enabling robust hydrogen-bonding interactions. The trifluoromethyl substituents enhance lipophilicity and metabolic stability, while the dimethylamino group improves solubility and facilitates derivatization. This combination delivers a bench-stable, moisture-tolerant reagent ideal for supramolecular synthesis and ligand design.
This thiourea derivative serves as a versatile building block in medicinal chemistry, leveraging the electron-withdrawing trifluoromethyl groups to enhance metabolic stability and modulate lipophilicity. The cyclohexylamine scaffold provides a rigid, chiral framework ideal for structure-activity studies. Its thiourea moiety enables hydrogen bonding interactions and facilitates formation of metal complexes or covalent adducts. Bench-stable and amenable to standard purification methods, it functions effectively in multistep synthesis and high-throughput screening workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364
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Lot numbers can be found on the outside label of a product: