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Structure of 1256256-45-7
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This boronate ester features a tert-butyl carbamate-protected amine appended to a fluoro-substituted aryl group, enabling stable coupling in Suzuki-Miyaura reactions. The tetramethyl-dioxaborolane moiety ensures high reactivity and shelf stability under standard conditions.
tert-Butyl (3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate serves as a stable, bench-friendly boron building block for Suzuki-Miyaura cross-coupling reactions. The trifluoroborate moiety enables efficient coupling with aryl halides and pseudohalides under mild conditions, while the tert-butoxycarbonyl (Boc) group provides orthogonal protection for amine functionalities. Its high functional group tolerance and ease of purification make it ideal for constructing complex pharmaceutical intermediates and heterocyclic scaffolds in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: