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Structure of 1256789-55-5
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2-Bromo-5-methoxyisonicotinic acid features a bromine atom at the 2-position and a methoxy group at the 5-position of the pyridine ring, delivering enhanced electron-withdrawing character and improved solubility in polar organic solvents. This structural configuration supports efficient coupling reactions in medicinal chemistry and materials synthesis, particularly in Suzuki-Miyaura and Buchwald-Hartwig transformations.
2-Bromo-5-methoxyisonicotinic acid serves as a versatile building block for the synthesis of heterocyclic scaffolds and bioactive molecules. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality supports direct derivatization or coupling protocols. The methoxy substituent enhances solubility and modulates electronic properties, offering predictable reactivity in standard synthetic workflows. This compound exhibits bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: