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Structure of 1256806-73-1
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2-Bromo-5-fluoro-3-methoxypyridine features a strategically positioned bromo and fluoro substituent on a pyridine core, enabling selective cross-coupling reactions. The methoxy group enhances solubility and modulates electronic properties. This bench-stable heterocycle serves as a key intermediate in the synthesis of bioactive compounds and functional materials.
2-Bromo-5-fluoro-3-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluorine and methoxy substituents offer tunable electronic effects and steric profiles. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: