2-Bromo-3-methoxypyridine

Name: 2-Bromo-3-methoxypyridine
Brand: ChemScene
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CAS No. 24100-18-3
Cat. No. CS-W007501
Purity≥97%
MDL No.MFCD01570896

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 24100-18-3

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Description

2-Bromo-3-methoxypyridine features a pyridine core functionalized with a bromine atom at the 2-position and a methoxy group at the 3-position, enabling selective cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the methoxy substituent enhances solubility and modulates reactivity. This compound serves as a key intermediate in medicinal chemistry and agrochemical synthesis.

Application

2-Bromo-3-methoxypyridine serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. Its bromine moiety enables reliable Suzuki, Stille, and Negishi couplings, while the methoxy group provides moderate electronic modulation and orthogonal reactivity. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in late-stage functionalization strategies for heterocyclic scaffolds.

General Information

CAS No. 24100-18-3
Cat. No. CS-W007501
Purity ≥97%
MDL No. MFCD01570896
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆BrNO
Molecular Weight 188.02
Synonym(s) None
SMILES COC1=CC=CN=C1Br

Computational Chemistry Data

TPSA 22.12
LogP 1.8527
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-3-methoxypyridine

CAS No. 24100-18-3

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