6-Bromo-4-chloro-7-methoxyquinazoline

Name: 6-Bromo-4-chloro-7-methoxyquinazoline
Brand: ChemScene
Availability: OutOfStock
Rating: 5 (1 reviews)

CAS No. 1256955-27-7
Cat. No. CS-0150558
Purity≥95%
MDL No.MFCD21362985

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-4-chloro-7-methoxyquinazoline|CS-0150558

Structure of 1256955-27-7

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General Information

CAS No. 1256955-27-7
Cat. No. CS-0150558
Purity ≥95%
MDL No. MFCD21362985
Storage Sealed in dry,2-8℃
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₆BrClN₂O
Molecular Weight 273.51
Synonym(s) Quinazoline, 6-bromo-4-chloro-7-methoxy-
SMILES COC1=C(C=C2C(=C1)N=CN=C2Cl)Br

Synthesis

Route1
- In-stock
  
  950577-05-6
- ~62%
- 1256955-27-7
References
- EXELIXIS, INC.; ANAND, Neel, Kumar; BLAZEY, Charles, M.; BOWLES, Owen, Joseph; BUHR, Chris, Allen; BUSSENIUS, Joerg; CURTIS, Jeffry, Kimo; DEFINA, Steven, Charles; DUBENKO, Larisa; HARRIS, Jason, R.; JACKSON-UGUETO, Eileen; JOSHI, Anagha; KIM, Angie, Inyoung; TSUHAKI, Amy, Lew; MA, Sunghoon; MANALO, Jean-claire, Limun; NG, Stephanie; PETO, Csaba, J.; RICE Kenneth D.; TSANG, Tsze, H.; ZAHARIA, Cristiana, A. Patent: WO2010/135524 A1, 2010 ; Location in patent: Page/Page column 190 ; WO 2010/135524 A1
Route2
- In-stock
  
  169044-96-6
- ~%
- 1256955-27-7
References
- EXELIXIS, INC.; RICE, Kenneth; FOSTER, Paul Patent: WO2012/71519 A1, 2012 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 35.01
LogP 3.0543
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

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6-Bromo-4-chloro-7-methoxyquinazoline

CAS No. 1256955-27-7

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General Information

Synthesis

References