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Structure of 1257535-45-7
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7-Bromo-6-methyl-1H-indazole is a heterocyclic scaffold featuring a bromine substituent at the 7-position and a methyl group at the 6-position, offering enhanced electron density and steric profile. This configuration enables selective coupling in transition-metal-catalyzed reactions, particularly Suzuki-Miyaura and Buchwald-Hartwig transformations. The molecule demonstrates excellent bench stability and solubility in common organic solvents, facilitating integration into complex synthetic sequences for medicinal chemistry and materials development.
7-Bromo-6-methyl-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically active scaffolds. The bromine atom facilitates palladium-catalyzed cross-coupling reactions, while the methyl group provides steric and electronic modulation. This compound exhibits excellent bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for modular synthesis of drug candidates and advanced intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: