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1-(3-Aminopropyl)-1H-pyrrole-2,5-dione (hydrochloride)

  • CAS No. 1257852-74-6

  • Cat. No. CS-0091673
  • Molecule weight190.63
  • Purity≥97%
  • MDL No.MFCD11519188

*For research and further manufacturing use only, not for direct human use.

1-(3-Aminopropyl)-1H-pyrrole-2,5-dione (hydrochloride)|CS-0091673

Structure of 1257852-74-6

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General Information

  • CAS No. 1257852-74-6
  • Cat. No. CS-0091673
  • Purity ≥97%
  • MDL No. MFCD11519188
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁ClN₂O₂
  • Molecular Weight 190.63
  • Synonym(s) None
  • SMILES O=C(C=C1)N(CCCN)C1=O.Cl

Description

This pyrrolidine derivative features a pendant amine group for conjugation, enabling integration into bioactive scaffolds. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating use in peptide coupling and medicinal chemistry workflows.

Application

1-(3-Aminopropyl)-1H-pyrrole-2,5-dione (hydrochloride) serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient conjugation and scaffold elaboration. The pendant amine facilitates nucleophilic reactions and derivatization, while the electron-deficient pyrrolinedione core supports Diels–Alder cycloadditions and Michael additions. Its hydrochloride salt enhances bench stability and solubility, simplifying handling and purification in standard laboratory workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   63.4
  • LogP   -0.318
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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