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Structure of 1260242-01-0
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This iodinated benzyl alcohol features a methyl group at the ortho position relative to the hydroxymethyl moiety, enhancing electronic and steric control. The pendant iodine enables direct functionalization via cross-coupling reactions. The molecule exhibits bench-stable handling characteristics under standard conditions and integrates readily into synthetic sequences requiring halogen-directed derivatization.
(5-Iodo-2-methylphenyl)methanol serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its iodide functionality exhibits high reactivity in standard Suzuki, Stille, and Negishi couplings, while the benzylic alcohol group provides a handle for further derivatization or protection. The molecule demonstrates good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: