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Structure of 612833-45-1
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Ethyl 5-iodo-2-methylbenzoate features a para-iodinated benzene ring flanked by an ethyl ester and a methyl group, enabling direct functionalization in cross-coupling reactions. The iodide moiety provides high reactivity under palladium catalysis, while the ester and methyl substituents offer stability and tunable electronic effects. This compound serves as a robust scaffold for synthesizing complex aromatic architectures in medicinal chemistry and materials science.
Ethyl 5-iodo-2-methylbenzoate serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation. The iodide group exhibits high reactivity in palladium-catalyzed coupling processes, while the ester and methyl functionalities offer orthogonal handles for further derivatization. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: