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Structure of 126058-97-7
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3,5-Difluoro-4-hydroxyaniline features a hydroxyl group flanked by two fluorine substituents at the 3 and 5 positions, creating an electron-deficient aromatic system ideal for coupling reactions. The para-hydroxy functionality enables direct integration into bioconjugation workflows, while the difluoro substitution enhances metabolic stability and modulates electronic properties for advanced pharmaceutical intermediates.
3,5-Difluoro-4-hydroxyaniline serves as a valuable building block for fluorinated aromatic scaffolds in medicinal chemistry. The hydroxyl group enables direct coupling reactions or derivatization, while the ortho-fluorine substituents facilitate nucleophilic aromatic substitution under mild conditions. Its bench-stable nature and compatibility with standard protection strategies make it well-suited for multi-step synthesis of heterocyclic compounds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: